X-Health.show - meet the future of healthcare
The X-Health.show brings to you brilliant minds behind programming living cells, tech that detects pre-term delivery in seconds, brain-computer interface or apps that employ AI to match you, your disease with the best treatment.
For the eXtra Health of the future.
You’ll meet visionaries from Switzerland who push the boundaries of healthcare.
Engineers who teamed up with doctors, scientists turned CEOs, doctors programming AI-powered apps, researchers who abandoned university labs to improve your health.
You’ll hear stories of promising startups founders and successful serial entrepreneurs.
Patients who imagine a better way.
You’ll
learn about new disease treatments
understand how AI-driven health tech can improve your life
grasp the way founders innovate
or even, get inspired to jumpstart innovation at your company.
Luckily, the X-Health.show is based in Switzerland, the most innovative country in the world according to World Intellectual Property Organization. For the 12th consecutive year. No wonder when the abundance of funds for innovation meets the ability to commercialize the discoveries.
With notable research institutions situated nearby top pharmaceutical companies, there’s more to expect. More medical innovations, break-through femtech, life changing biotech, developments in digital health, genetic engineering, and wearables, such as smart ring, blood pressure measurement on your wrist or ECG in your pyjama.
Follow the show to meet these amazing innovators.
X-Health.show - meet the future of healthcare
Replacing Chemotherapy with a Gentler Process: Dr. Danielle Villars, ATLyphe
How one approaches the goal of replacing chemotherapy with a gentler process? Where does the “we can do it” start? How do you get to the point where your process shows no side effects in the pre-clinical phase, in animals? And when will clinical trials start – in patients?
In this episode, you’ll hear about
- how are blood cells produced
- acute myeloid leukemia
- hematopoietic stem cell transplantation or bone marrow transplant procedure
- how to replace chemotherapy in the conditioning stage
ATLyphe is a Swiss Startup, a spin-off from the ETH Zurich and the University of Zurich. They developed a T cell engager and activator for safer, precise conditioning before hematopoietic stem cell transplantation in leukemia.
My guest today is Dr. Danielle Villars, the CEO of ATLYphe, a biologist who completed her PhD in cancer biology. She already proved she is a high achiever – before committing to science-backed entrepreneurship and bringing this new process to patients, she broke four national records as an Olympic swimmer for Switzerland.
Here’s more about ATLyphe:
https://www.atlyphe.com/
Please note, the treatment is not yet available for patients.
Timestamps:
0:00 Dr. Danielle Villars and ATLyphe
1:18 Aim: No Chemotherapy Side Effects
4:23 How Are Blood Cells Produced
6:28 Gene Mutation in Acute Myeloid Leukemia
11:00 How is Acute Myeloid Leukemia Treated Currently
13:06 What Is the Hematopoietic Stem Cell Transplantation Process
16:06 What is Conditioning before Blood Transplantation
20:40 Immunotherapeutic Approach in Place of Chemotherapy
27:16 What is Graft vs Host Disease
29:27 Beginnings of ALY117 Immunotherapy for Conditioning
37:21 Study Pathway before Patients Can Receive ALY117
45:20 Thank You, Follow ATLyphe
45:48 Follow X-Health.show, Disclaimer
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The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
